People

Current members

Lars Behrendt, assistant professor

Linhong Xiao, postdoc (started March 2020)

Yuan Cui, PhD student (started May 2020)

The focus of Yuan’s PhD project will be on developing a microfluidic platform enabling the metabolism measurement for ecologically relevant single marine phytoplankton cells, and assessing the singular and combined impacts of environmental change on single cells with a focus on heterogeneity within populations.

Short CV

  • Since 2020, PhD student in Environmental Toxicology, Uppsala University
  • 2019, MSc in Environmental Engineering, ETH Zürich (Switzerland)
  • 2017, BSc in Environmental Engineering, Jilin University (China)

Armanu Emanuel, Master student (started September 2020)

My master thesis involves the analysis of bacteria Vibrio natriegens, an ultrafast-growing bacteria and next-generation workhorse for biotechnology. Using a microfluidic device called the ‘‘mother machine’’, I aim to observe the changes that occurs in single-cell growth inside the dead-end microchannels of this chip. This device allows me to investigate single-cell physiological parameters like gene expression, growth rates and response to foreign chemicals on the single cell level. Using an automated framework I try to solve and facilitate the analysis of phase contrast images taken in high-throughput within these devices. Doing this research will advance our understanding of the role of environmental chemicals on single bacterial cells.

Chiara Buonfrate, Master student (started October 2020)

In my master project I will explore stress effects on single cells of the diatom P. tricornutum. My aim is to assess the heterogeneity in stress responses among single cells. To do this I will build advanced microfluidics devices that monitor single cell growth and compare these results to standard bulk growth methods. Next, I aim to examine the effect of chemical stress and to investigate the phenotypic plasticity among single cells using high-throughput automated fluorescence microscopy. My long-term goal is to deepen our understanding on the ecological role of single-cell plasticity in phytoplankton bloom dynamics. 

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